Advancing research, education, and clinical practice in precision medicine
Dr. Jessica Lang was recently awarded a Department of Defense Ovarian Cancer Research Program Pilot Award focused on oncogene over-expression through the intersection of copy number amplifications and super-enhancer gains in ovarian cancer. High-grade serous ovarian cancer is amongst the highest copy number altered tumors, and targeted therapies have thus been challenging to predict. In addition, …
Congratulations to Dr. Bryn Webb and her colleagues for their recent publication in Nature Genetics! The paper, titled “Noncoding variants alter GATA2 expression in rhombomere 4 motor neurons and cause dominant hereditary congenital facial paresis”, can be read here. This paper is an early example of using whole genome sequencing to define the pathogenesis of …
The Texas-based non-profit organization Elijah’s Project for Hope has awarded Bryn Webb, MD, a two-year research grant in the amount of $282,553 to investigate a rare genetic disorder that results from mutations in the WARS2 gene. The research period is January 1, 2023, through December 31, 2024. Webb is an associate professor in the Division of Genetics and Metabolism in …
Congratulations to Dr. Muhammed Murtaza and his team for their recent publication in Science Translational Medicine! Fragment patterns in tumor DNA offer a roadmap to diagnose patients with cancer. A new machine learning platform can distinguish patients with cancer by analyzing patterns in fragments of cell-free DNA – pieces of tumor genetic material in the blood …
Follow this link to view Dr. Stephen Meyn’s presentation: